Preclinical characterization of recombinant human tissue kallikrein-1 as a novel treatment for type 2 diabetes mellitus.
Modulation of the kallikrein-kinin system (KKS) has been shown to have beneficial effects on glucose homeostasis and several other physiological responses relevant to the progression of copyright Adjustable Rear Arm type 2 diabetes mellitus (T2D).The importance of bradykinin and its receptors in mediating these responses is well documented, but the